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DNA ligases seal five′-PO4 and three′-OH polynucleotide finishes by means of 3 nucleotidyl transfer steps involving ligase-adenylate and DNA-adenylate intermediates. DNA ligases are crucial guardians of genomic integrity, and ligase dysfunction underlies human genetic ailment syndromes. Crystal buildings of DNA ligases sure to nucleotide and nucleic acid substrates have https://ligaz-bet-sports-betting97406.blogolenta.com/24933643/fascination-about-info-https-ligaz-bet

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